rs115873798 - WWC1

Magnitude 2.2 · 1 study on file

Reported associations

• GWAS in people of Middle Eastern descent reveals a locus protective of kidney function-a cross-sectional study - Unknown journal (n.d.) · Unknown authors · PubMed 35227251

  ABSTRACT: Background Type 2 diabetes is one of the leading causes of chronic kidney failure, which increases globally and represents a significant threat to public health. People from the Middle East represent one of the largest immigrant groups in Europe today. Despite poor glucose regulation and high risk for early-onset insulin-deficient type 2 diabetes, they have better kidney function and lower rates of all-cause and cardiovascular-specific mortality compared with people of European ancestry. Here, we assessed the genetic basis of estimated glomerular filtration rate (eGFR) and other metabolic traits in people of Iraqi ancestry living in southern Sweden. Methods Genome-wide association study (GWAS) analyses were performed in 1201 Iraqi-born residents of the city of Malmö for eGFR and

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