rs115698394 - KRT18P54 - TARS2P1

Magnitude 4.5 · 1 study on file

Reported associations

  • A Genome-Wide Association Study of Serum Metabolite Profiles in Septic Shock Patients - Unknown journal (n.d.) · Unknown authors · PubMed 38239409

    ABSTRACT: OBJECTIVES: We sought to assess whether genetic associations with metabolite concentrations in septic shock patients could be used to identify pathways of potential importance for understanding sepsis pathophysiology. DESIGN: Retrospective multicenter cohort studies of septic shock patients. SETTING: All participants who were admitted to 27 participating hospital sites in three countries (Australia, New Zealand, and the United Kingdom) were eligible for inclusion. PATIENTS: Adult, critically ill, mechanically ventilated patients with septic shock (n = 230) who were a subset of the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock trial (ClinicalTrials.gov number: NCT01448109). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: A genome-wide associa


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