rs115487049 - GCFC2 - SUCLA2P2

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia - Unknown journal (n.d.) · Unknown authors · PubMed 34380480

  ABSTRACT: Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in populations of European ancestry (EUR), potentially missing important biological insights. It is important to perform 5 GWASs in non-European populations. Methods To identify novel schizophrenia risk loci, we conducted a GWAS in Han Chinese population (3493 cases and 4709 controls). We then performed a large-scale meta-analysis (a total of 143,438 subjects) through combining our results with previous GWASs conducted in EAS and EUR. In addition, we also carried out comprehensive post-GWAS analysis, including heritability partitioning, enrichment of schizophrenia associations in tissues and cell types, trancscriptome-wide

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