rs115069403 - LINC02124 - HS3ST6
Magnitude 4.5 · 1 study on file
Reported associations
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Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci - Unknown journal (n.d.) · Unknown authors · PubMed 38469033
ABSTRACT: Background Mood disorders such as major depressive and bipolar disorders, along with posttraumatic stress disorder (PTSD), schizophrenia (SCZ), and other psychotic disorders, constitute serious mental illnesses (SMI) and often lead to inpatient psychiatric care for adults. Risk factors associated with increased hospitalization rate in SMI (H-SMI) are largely unknown but likely involve a combination of genetic, environmental, and socio-behavioral factors. We performed a genome-wide association study in an African American cohort to identify possible genes associated with hospitalization due to SMI (H-SMI). Methods Patients hospitalized for psychiatric disorders (H-SMI; n=690) were compared with demographically matched controls (n=4467). Quality control and imputation of genome-wid
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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genetic mental illness hospitalization risk Moderate
Rs115069403 T allele associated with higher hospitalization rates in serious mental illness, indicating need for tailored clinical monitoring
If diagnosed with serious mental illness, inform psychiatrist of this genetic finding
Screening
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mental health baseline assessment and monitoring Moderate
Rs115069403 T allele associated with higher hospitalization rates in serious mental illnesses, suggesting more severe outcomes in risk carriers
Baseline psychological assessment in early adulthood; annual mental health check-ins