rs11478283 - ZHX3
Magnitude 4.5 · 1 study on file
Reported associations
-
Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease - Unknown journal (n.d.) · Unknown authors · PubMed 35884923
ABSTRACT: A comprehensive understanding of gene-diet interactions is necessary to establish proper dietary guidelines to prevent and manage cardio-cerebrovascular disease (CCD). We investigated the role of genetic variants associated with dyslipidaemia (DL) and their interactions with macro-nutrients for cardiovascular disease using a large-scale genome-wide association study of Korean adults. A total of 58,701 participants from a Korean genome and epidemiology study were included. Their dietary intake was assessed using a food frequency questionnaire. Dyslipidaemia was defined as total cholesterol (TCHL) ≥ 240 mg/dL, high-density lipoprotein (HDL) < 40 mg/dL, low-density lipoprotein (LDL) ≥ 160 mg/dL, triglycerides (TG) ≥ 200 mg/dL, or dyslipidaemia history. Their nutrient intake wa
Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.
Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Bloodwork
-
total cholesterol levels Moderate
This SNP is associated with elevated total cholesterol, a major cardiovascular risk factor
Check total cholesterol annually or as recommended by clinician
Diet
-
cholesterol-reducing dietary pattern Moderate
Genetic predisposition to elevated cholesterol warrants dietary modifications for cardiovascular health
Consider Mediterranean or DASH diet pattern; reduce saturated fat intake