rs11466328 - TGFB1

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic Associations with Gestational Length and Spontaneous Preterm Birth - Unknown journal (n.d.) · Unknown authors · PubMed 28877031

  ABSTRACT: Background Despite evidence that genetic factors contribute to gestational length and preterm birth, robust associations with genetic variants have not been identified. We hypothesized that analyzing larger data sets with gestational length information by genomewide association would reveal trait-influencing variants. Methods We performed a genomewide association study in a discovery data set of 43,568 women of European ancestry from 23andMe, Inc., for gestational length as a continuous trait and for term or preterm (<37 weeks) birth as a dichotomous outcome. We used three Nordic data sets (8,643 women) for replication of 14 genomic loci achieving either genomewide (P < 5×10-8) or suggestive association (P < 1×10-6). Results In the discovery stage, for gestational length, four

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