rs113497890 - LCOR

Magnitude 4.5 · 1 study on file

Reported associations

• Novel loci and Mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys - Unknown journal (n.d.) · Unknown authors · PubMed 34047840

  ABSTRACT: Puberty is a complex developmental process that varies considerably among individuals and populations. Genetic factors explain a large proportion of the variability of several pubertal traits. Recent genome-wide association studies (GWAS) have identified hundreds of variants involved in traits that result from body growth, like adult height. However, they do not capture many genetic loci involved in growth changes over distinct growth phases. Further, such GWAS have been mostly performed in Europeans, but it is unknown how these findings relate to other continental populations. In this study, we analyzed the genetic basis of three pubertal traits; namely, peak height velocity (PV), age at PV (APV) and height at APV (HAPV). We analyzed a cohort of 904 admixed Chilean children and

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