rs113283269 - RPL23AP91 - CCL22

Magnitude 2.2 · 1 study on file

Reported associations

• A genome-wide association study of asthma hospitalizations in adults - Unknown journal (n.d.) · Unknown authors · PubMed 32890573

  ABSTRACT: Background: Little is known about genetic determinants of severe asthma exacerbations. Objectives: We aimed to identify genetic variants associated with asthma hospitalizations. Methods: Genome-wide association study of asthma hospitalizations in 34,167 white British adults with asthma, of whom 1,658 (cases) had at least one asthma-related hospitalization. This analysis was conducted using logistic regression under an additive genetic model, adjusting for age, sex, body mass index, smoking status, and the first five principal components derived from genotypic data. We then analyzed data from two cohorts of Latino children and adolescents for replication and conducted quantitative trait locus and functional annotation analyses. Results: At the chromosome 6p21.3 locus, the single n

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