rs113249637 - NDUFA8

Magnitude 2.2 · 1 study on file

Reported associations

• Large-Scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew - Unknown journal (n.d.) · Unknown authors · PubMed 33836062

  ABSTRACT: Abstract The human cerebral hemispheres show a left-right asymmetrical torque pattern, which has been claimed to be absent in chimpanzees. The functional significance and developmental mechanisms are unknown. Here, we carried out the largest-ever analysis of global brain shape asymmetry in magnetic resonance imaging data. Three population datasets were used, UK Biobank (N = 39 678), Human Connectome Project (N = 1113), and BIL&GIN (N = 453). At the population level, there was an anterior and dorsal skew of the right hemisphere, relative to the left. Both skews were associated independently with handedness, and various regional gray and white matter metrics oppositely in the two hemispheres, as well as other variables related to cognitive functions, sociodemographi

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