rs113209956 - RN7SKP120 - TUSC1

Magnitude 2.8 · 1 study on file

Reported associations

• Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study. - JAMA psychiatry (2021) · Meier SM, Trontti K, Purves KL, Als TD, Grove J, Laine M, Pedersen MG, Bybjerg-Grauholm J, Bækved-Hansen M, Sokolowska E, Mortensen PB, Hougaard DM, Werge T, Nordentoft M, Breen G, Børglum AD, Eley TC, Hovatta I, Mattheisen M, Mors O · PubMed 31116379

  Anxiety and stress-related disorders are among the most common mental disorders. Although family and twin studies indicate that both genetic and environmental factors play an important role underlying their etiology, the genetic underpinnings of anxiety and stress-related disorders are poorly understood. To estimate the single-nucleotide polymorphism-based heritability of anxiety and stress-related disorders; to identify novel genetic risk variants, genes, or biological pathways; to test for pleiotropic associations with other psychiatric traits; and to evaluate the association of psychiatric comorbidities with genetic findings. This genome-wide association study included individuals with various anxiety and stress-related diagnoses and controls derived from the population-based Lundbeck F

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