rs113140904 - SEMA5A, SNHG18

Magnitude 2.0 · 1 study on file

Reported associations

• Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations - Journal of thrombosis and haemostasis : JTH (2022) · Temprano-Sagrera G, Sitlani CM, Bone WP, Martin-Bornez M, Voight BF, Morrison AC, Damrauer SM, de Vries PS, Smith NL, Sabater-Lleal M · PubMed 35285134

  ABSTRACT: Abstract Background Multi‐phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. Objectives To discover novel genetic associations by combining summary data of correlated hemostatic traits and disease events. Methods Summary statistics from genome wide‐association studies (GWAS) from seven hemostatic traits (factor VII [FVII], factor VIII [FVIII], von Willebrand factor [VWF] factor XI [FXI], fibrinogen, tissue plasminogen activator [tPA], plasminogen activator inhibitor 1 [PAI

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