rs1129770 - CMYA5

Magnitude 2.2 · 1 study on file

Reported associations

• Genetic variants affecting bone mineral density and bone mineral content at multiple skeletal sites in Hispanic children - Unknown journal (n.d.) · Unknown authors · PubMed 31790847

  ABSTRACT: Context: Osteoporosis is a major public health burden with significant economic costs. However, the correlates of bone health in Hispanic children are understudied. Objective: We aimed to identify genetic variants associated with bone mineral density (BMD) and bone mineral content (BMC) at multiple skeletal sites in Hispanic children. Methods: We conducted a cross-sectional genome-wide linkage analysis, genome-wide and exome-wide association analysis of BMD and BMC. The Viva La Familia Study is a family-based cohort with a total of 1,030 Hispanic children (4-19 years old at baseline) conducted in Houston, TX. BMD and BMC were measured by Dual-energy X-ray absorptiometry. Results: Significant heritability were observed for BMC and BMD at multiple skeletal sites ranging between 4

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