rs112717154 - LINC01213

Magnitude 2.2 · 1 study on file

Reported associations

• Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. - Circulation. Arrhythmia and electrophysiology (2020) · Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M, Munroe PB · PubMed 31607149

  Early prediction of cardiovascular risk in the general population remains an important issue. The T-wave morphology restitution (TMR), an ECG marker quantifying ventricular repolarization dynamics, is strongly associated with cardiovascular mortality in patients with heart failure. Our aim was to evaluate the cardiovascular prognostic value of TMR in a UK middle-aged population and identify any genetic contribution. We analyzed ECG recordings from 55 222 individuals from a UK middle-aged population undergoing an exercise stress test in UK Biobank (UKB). TMR was used to measure ventricular repolarization dynamics, exposed in this cohort by exercise (TMR during exercise, TMR ) and recovery from exercise (TMR during recovery, TMR ). The primary end point was cardiovascular events; secondary

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