rs112673195 - LINC02422

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic Contributions to Urgency Urinary Incontinence in Women - Unknown journal (n.d.) · Unknown authors · PubMed 25524241

  ABSTRACT: Purpose To identify genetic variants associated with urgency urinary incontinence (UUI) in post-menopausal women. Materials and Methods A two-stage genome wide association analysis was conducted to identify variants associated with UUI. The Women's Health Initiative-Genomics & Randomized Trials Network (GARNET) sub-study with 4,894 genotyped post-reproductive white women was randomly split into independent discovery and replication cohorts. Genome-wide imputation was performed using IMPUTE2 with the 1000-Genomes-ALL-Phase-I integrated variant set as a reference. Controls reported no UUI at enrollment or follow-up; cases reported monthly or greater UUI and leaked sufficiently to wet/soak underpants/clothes. Logistic regression models were used to predict UUI case versus control

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