rs112595563 - DUS2

Magnitude 2.2 · 1 study on file

Reported associations

• Genetics of Blood Lipids Among ~300,000 Multi-Ethnic Participants of the Million Veteran Program - Unknown journal (n.d.) · Unknown authors · PubMed 30275531

  ABSTRACT: The Million Veteran Program (MVP) was established in 2011 as a national research initiative to determine how genetic variation influences the health of U.S. military veterans. We genotyped 312,571 MVP participants using a custom biobank array and linked the genetic data to laboratory and clinical phenotypes extracted from electronic health records covering a median of 10.0 years of follow-up. Among 297,626 veterans with at least 1 blood lipid measurement including 57,332 blacks and 24,743 Hispanics, we tested up to ~32 million variants for association with lipid levels and identified 118 novel genome-wide significant loci after meta-analysis with data from the Global Lipids Genetics Consortium (total N > 600,000). Through a focus on mutations predicted to result in a loss of gene

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