rs112545364 - ADA, PKIG

Magnitude 2.2 · 1 study on file

Reported associations

• Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults - Unknown journal (n.d.) · Unknown authors · PubMed 32641083

  ABSTRACT: Background The molecular factors which control circulating levels of inflammatory proteins are not well understood. Furthermore, association studies between molecular probes and human traits are often performed by linear model-based methods which may fail to account for complex structure and interrelationships within molecular datasets. Methods In this study, we perform genome- and epigenome-wide association studies (GWAS/EWAS) on the levels of 70 plasma-derived inflammatory protein biomarkers in healthy older adults (Lothian Birth Cohort 1936; n = 876; Olink® inflammation panel). We employ a Bayesian framework (BayesR+) which can account for issues pertaining to data structure and unknown confounding variables (with sensitivity analyses using ordinary least squares- (OLS) a

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