rs1124933 - RNU7-137P - Y_RNA

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease - Unknown journal (n.d.) · Unknown authors · PubMed 33111402

  ABSTRACT: Background: There are currently no treatments that stop or slow the progression of Parkinson's disease (PD). Case-control genome-wide association studies have identified variants associated with disease risk, but not progression. The objective of the current study was to identify genetic variants associated with PD progression. Methods: We analyzed 3 large longitudinal cohorts: Tracking Parkinson's, Oxford Discovery, and the Parkinson's Progression Markers Initiative. We included clinical data for 3364 patients with 12,144 observations (mean follow-up 4.2 years). We used a new method in PD, following a similar approach in Huntington's disease, in which we combined multiple assessments using a principal components analysis to derive scores for composite, motor, and cogniti

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