rs112363595 - ZIM2-AS1

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-Wide Association Study Identifies Candidate Loci Associated with Opioid Analgesic Requirements in the Treatment of Cancer Pain - Unknown journal (n.d.) · Unknown authors · PubMed 36230616

  ABSTRACT: Simple Summary Pain is experienced by ~55% of patients who undergo anti-cancer treatment. However, many genetic factors that are involved in the efficacy of opioid analgesics in the treatment of cancer pain remain unidentified. The aim of our genome-wide association study (GWAS) was to comprehensively explore genetic variations that are associated with opioid analgesic requirements in the treatment of cancer pain. We identified several single-nucleotide polymorphisms (SNPs) that are associated with opioid analgesic requirements, two of the most potent of which were the rs1283671 and rs1283720 SNPs in the ANGPT1 gene region, and SNPs in the SLC2A14 gene were also associated with the phenotype. These results indicate that these SNPs in the ANGPT1 and SLC2A14 genes could serve as ma

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