rs11230977 - SCGB1D1 - SCGB2A1

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide admixture and association analysis identifies African ancestry specific risk loci of eosinophilic esophagitis in African American - Unknown journal (n.d.) · Unknown authors · PubMed 36400179

  ABSTRACT: Rationale: Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease. Multiple genetic risk factors linked to EoE have been identified; however, these studies have been primarily focused on populations of European ancestry. There is a lack of studies leveraging the genetic architecture of Black or African American (AA) populations for the identification of loci involved in EoE susceptibility. Herein, we present admixture mapping (AM) and genome-wide association analysis (GWAS) of EoE using the participants of AA populations. Methods: We conducted AM and GWAS of EoE using 137 EoE cases and 1465 healthy controls from AA population. Samples were genotyped using the Multi-Ethnic Genotyping Array (MEGA). Genotype imputation was carried out with the CAAPA reference pane

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