rs11228583 - SMIM38 - MYEOV

Magnitude 2.8 · 1 study on file

Reported associations

• Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer - Unknown journal (n.d.) · Unknown authors · PubMed 24740154

  ABSTRACT: Prostate cancer is the most common non-skin cancer and the second leading cause of cancer related mortality for men in the United States. There is strong empirical and epidemiological evidence supporting a stronger role of genetics in early-onset prostate cancer. We performed a genome-wide association scan for early-onset prostate cancer. Novel aspects of this study include the focus on early-onset disease (defined as men with prostate cancer diagnosed before age 56 years) and use of publically available control genotype data from previous genome-wide association studies. We found genome-wide significant (p<5×10−8) evidence for variants at 8q24 and 11p15 and strong supportive evidence for a number of previously reported loci. We found little evidence for individual or systemat

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