rs11225247 - TMEM123

Magnitude 2.0 · 1 study on file

Reported associations

• Genetic variants associated with vein graft stenosis after coronary artery bypass grafting. - The heart surgery forum (2016) · Shah AA, Haynes C, Craig DM, Sebek J, Grass E, Abramson K, Hauser E, Gregory SG, Kraus WE, Smith PK, Shah SH · PubMed 25881214

  Vein graft stenosis after coronary artery bypass grafting (CABG) is common. Identifying genes associated with vein graft stenosis after CABG could reveal novel mechanisms of disease and discriminate patients at risk for graft failure. We hypothesized that genome-wide association would identify these genes. We performed a genome-wide association study on a subset of patients presenting for cardiac catheterization for concern of ischemic heart disease, who also underwent CABG and subsequent coronary angiography after CABG for clinical indications (n = 521). Cases were defined as individuals with ≥50% stenosis in any vein graft on any cardiac catheterization, and controls were defined as those who did not have vein graft stenosis on any subsequent cardiac catheterization. Multivariable logi

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