rs11223971 - LINC02706 - LINC02714

Magnitude 2.2 · 1 study on file

Reported associations

• Cardiac Troponin T and Troponin I in the General Population - Unknown journal (n.d.) · Unknown authors · PubMed 31014085

  ABSTRACT: Supplemental Digital Content is available in the text. Background: There is great interest in widening the use of high-sensitivity cardiac troponins for population cardiovascular disease (CVD) and heart failure screening. However, it is not clear whether cardiac troponin T (cTnT) and troponin I (cTnI) are equivalent measures of risk in this setting. We aimed to compare and contrast (1) the association of cTnT and cTnI with CVD and non-CVD outcomes, and (2) their determinants in a genome-wide association study. Methods: High-sensitivity cTnT and cTnI were measured in serum from 19 501 individuals in Generation Scotland Scottish Family Health Study. Median follow-up was 7.8 years (quartile 1 to quartile 3, 7.1-9.2). Associations of each troponin with a composite CVD outcome (11

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