rs11199799 - RPL19P16 - LINC01153
Magnitude 2.2 · 1 study on file
Reported associations
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Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease - Unknown journal (n.d.) · Unknown authors · PubMed 35884923
ABSTRACT: A comprehensive understanding of gene-diet interactions is necessary to establish proper dietary guidelines to prevent and manage cardio-cerebrovascular disease (CCD). We investigated the role of genetic variants associated with dyslipidaemia (DL) and their interactions with macro-nutrients for cardiovascular disease using a large-scale genome-wide association study of Korean adults. A total of 58,701 participants from a Korean genome and epidemiology study were included. Their dietary intake was assessed using a food frequency questionnaire. Dyslipidaemia was defined as total cholesterol (TCHL) ≥ 240 mg/dL, high-density lipoprotein (HDL) < 40 mg/dL, low-density lipoprotein (LDL) ≥ 160 mg/dL, triglycerides (TG) ≥ 200 mg/dL, or dyslipidaemia history. Their nutrient intake wa
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Bloodwork
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HDL cholesterol level Moderate
rs11199799 is significantly associated with HDL cholesterol; periodic monitoring assesses cardiovascular risk and intervention response
Annual lipid panel including HDL-C measurement
Diet
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increase soluble fiber intake Moderate
rs11199799 affects HDL cholesterol levels; dietary fiber intake is associated with improved HDL-C
Aim for 25-30g soluble fiber daily from whole grains and legumes
Exercise
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aerobic exercise for HDL support Moderate
rs11199799 is associated with HDL cholesterol variation; aerobic exercise directly raises HDL-C levels
150 min/week moderate-intensity aerobic activity