rs11193561 - RNA5SP326 - LINC01435
Magnitude 2.2 · 1 study on file
Reported associations
-
Genome-Wide Association Study Link Novel Loci to Endometriosis - Unknown journal (n.d.) · Unknown authors · PubMed 23472165
ABSTRACT: Endometriosis is a common gynecological condition with complex etiology defined by the presence of endometrial glands and stroma outside the womb. Endometriosis is a common cause of both cyclic and chronic pelvic pain, reduced fertility, and reduced quality-of-life. Diagnosis and treatment of endometriosis is, on average, delayed by 7-10 years from the onset of symptoms. Absence of a timely and non-invasive diagnostic tool is presently the greatest barrier to the identification and treatment of endometriosis. Twin and family studies have documented an increased relative risk in families. To identify genetic factors that contribute to endometriosis we conducted a two-stage genome-wide association study (GWAS) of a European cohort including 2,019 surgically confirmed endometriosi
Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.
Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
-
endometriosis risk and screening strategy Moderate
Known genetic risk factors enable early symptom identification and clinical intervention planning
discuss symptom assessment and optimal screening modality (ultrasound, MRI, clinical) with gynecologist
Screening
-
endometriosis symptom awareness and clinical screening Moderate
rs11193561 A allele increases endometriosis susceptibility by 1.19-fold through genetic mechanisms
annual pelvic ultrasound or gynecology evaluation if symptomatic; discuss imaging with clinician