rs11174650 - PPM1H

Magnitude 2.2 · 1 study on file

Reported associations

  • Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults - Unknown journal (n.d.) · Unknown authors · PubMed 26632684

    ABSTRACT: Supplemental Digital Content is available in the text Abstract Olfactory dysfunction is common among older adults and affects their safety, nutrition, quality of life, and mortality. More importantly, the decreased sense of smell is an early symptom of neurodegenerative diseases such as Parkinson disease (PD) and Alzheimer disease. However, the genetic determinants for the sense of smell have been poorly investigated. We here performed the first genome-wide meta-analysis on the sense of smell among 6252 US older adults of European descent from the Atherosclerosis Risk in Communities (ARIC) study, the Health, Aging, and Body Composition (Health ABC) study, and the Religious Orders Study and the Rush Memory and Aging Project (ROS/MAP). Genome-wide association study analysis was per


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