rs111672076 - CACNA1I

Magnitude 2.0 · 1 study on file

Reported associations

• A General Dimension of Genetic Sharing across Diverse Cognitive Traits Inferred from Molecular Data - Unknown journal (n.d.) · Unknown authors · PubMed 32895543

  ABSTRACT: It has been known since 1904 that, in humans, diverse cognitive traits are positively inter correlated. This forms the basis for the general factor of intelligence (g). Here, we directly test whether there is a partial genetic basis for individual differences in g using data from seven different cognitive tests (N = 11,263 to N = 331,679) and genome-wide autosomal single nucleotide polymorphisms. A genetic g factor accounts for an average of 58.4% (SE = 4.8%) of the genetic variance in the cognitive traits, with the proportion varying widely across traits (range: 9% to 95%). We distill genetic loci that are broadly relevant for many cognitive traits (g) from loci associated specifically with individual cognitive traits. These results contribute to elucidating the etiology of a lo

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