rs11158418 - LINC00644 - ATP5F1AP4

Magnitude 4.5 · 1 study on file

Reported associations

• Population-based genetic effects for developmental stuttering - Unknown journal (n.d.) · Unknown authors · PubMed 35047858

  ABSTRACT: Summary Despite a lifetime prevalence of at least 5%, developmental stuttering, characterized by prolongations, blocks, and repetitions of speech sounds, remains a largely idiopathic speech disorder. Family, twin, and segregation studies overwhelmingly support a strong genetic influence on stuttering risk; however, its complex mode of inheritance combined with thus-far underpowered genetic studies contribute to the challenge of identifying and reproducing genes implicated in developmental stuttering susceptibility. We conducted a trans-ancestry genome-wide association study (GWAS) and meta-analysis of developmental stuttering in two primary datasets: The International Stuttering Project comprising 1,345 clinically ascertained cases from multiple global sites and 6,759 matched pop

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