rs111469561 - LINC01556 - KRT18P1
Magnitude 2.2 · 1 study on file
Reported associations
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Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections - Unknown journal (n.d.) · Unknown authors · PubMed 28928442
ABSTRACT: Infectious diseases have a profound impact on our health and many studies suggest that host genetics play a major role in the pathogenesis of most of them. We perform 23 genome-wide association studies for common infections and infection-associated procedures, including chickenpox, shingles, cold sores, mononucleosis, mumps, hepatitis B, plantar warts, positive tuberculosis test results, strep throat, scarlet fever, pneumonia, bacterial meningitis, yeast infections, urinary tract infections, tonsillectomy, childhood ear infections, myringotomy, measles, hepatitis A, rheumatic fever, common colds, rubella and chronic sinus infection, in over 200,000 individuals of European ancestry. We detect 59 genome-wide significant (P < 5 × 10−8) associations in genes with key roles
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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wart prevention and management plan with dermatologist Moderate
Genetic predisposition to plantar warts warrants proactive discussion of prevention and early intervention strategies
Lifestyle
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barefoot contact with public surfaces Moderate
Plantar warts result from HPV infection via direct skin contact; contaminated surfaces in pools, locker rooms, and communal areas increase transmission risk in genetically susceptible individuals
Wear protective footwear (shower shoes, sandals) in public pools, communal showers, locker rooms, and gym areas
Screening
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monthly foot inspection for lesions Moderate
Early detection of plantar warts enables prompt treatment before enlargement or spread to other areas
Inspect plantar surface and heels monthly; note any new growths, bumps, or discolored patches