rs11140773 - NTRK2

Magnitude 2.0 · 1 study on file

Reported associations

• The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls - Unknown journal (n.d.) · Unknown authors · PubMed 31926635

  ABSTRACT: Background Mood disorders (including major depressive disorder and bipolar disorder) affect 10-20% of the population. They range from brief, mild episodes to severe, incapacitating conditions that markedly impact lives. Despite their diagnostic distinction, multiple approaches have shown considerable sharing of risk factors across the mood disorders. Methods To clarify their shared molecular genetic basis, and to highlight disorder-specific associations, we meta-analysed data from the latest Psychiatric Genomics Consortium (PGC) genome-wide association studies of major depression (including data from 23andMe) and bipolar disorder, and an additional major depressive disorder cohort from UK Biobank (total: 185,285 cases, 439,741 controls; non-overlapping N = 609,424). Results Sev

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