rs11136645 - CSMD1

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide Association Study of Post-burn Scarring Identifies a Novel Protective Variant - Unknown journal (n.d.) · Unknown authors · PubMed 26366535

  ABSTRACT: Objective: To identify genetic variants associated with severity of post-burn hypertrophic scarring (HTS) using a genome-wide approach. Background: Risk of severe post-burn HTS is known to depend on race, but the genetic determinants of HTS are unknown. Methods: We conducted a genome-wide association study (GWAS) in a prospective cohort of adults admitted with deep-partial-thickness burns from 2007 through 2014. Scar severity was assessed over time using the Vancouver Scar Scale (VSS), and DNA was genotyped with a >500,000-marker array. We performed association testing of SNPs with minor allele frequency (MAF) >0.01 using linear regression of VSS height score on genotype adjusted for patient- and injury characteristics as well as population genetic structure. Array-wide significa

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