rs11114975 - PPFIA2

Magnitude 2.2 · 1 study on file

Reported associations

• Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior - Unknown journal (n.d.) · Unknown authors · PubMed 31467194

  ABSTRACT: INTRODUCTION: Across human societies and in both sexes, some 2 to 10% of individuals report engaging in sex with same-sex partners, either exclusively or in addition to sex with opposite-sex partners. Twin and family studies have shown that same-sex sexual behavior is partly genetically influenced, but previous searches for the specific genes involved have been underpowered to detect effect sizes realistic for complex traits. RATIONALE: For the first time, new large-scale datasets afford sufficient statistical power to identify genetic variants associated with same-sex sexual behavior (ever versus never had a same-sex partner), estimate the proportion of variation in the trait accounted for by all variants in aggregate, estimate the genetic correlation of same-sex sexual behavior

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