rs1110549 - UTP4

Magnitude 2.2 · 1 study on file

Reported associations

• Helicobacter pylori Treatment and Gastric Cancer Risk Among Individuals With High Genetic Risk for Gastric Cancer - Unknown journal (n.d.) · Unknown authors · PubMed 38809553

  ABSTRACT: Key Points Question Is genetic susceptibility for gastric cancer associated with the outcomes of its primary prevention strategies? Findings In this cohort study of more than 100 000 Chinese adults, a polygenic risk score associated with the risk of gastric cancer was derived. Helicobacter pylori treatment was associated with reduced gastric cancer risk for individuals with a high genetic risk during long-term follow-up but not for those with low genetic risk. Meaning The findings of this study support the benefits of H pylori treatment for individuals with a high genetic risk of gastric cancer and suggest the utilization of genetic susceptibility for implementing effective gastric cancer primary prevention. This cohort study examines whether outcomes of primary prevention stra

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.