rs11104632 - LINC02258 - RPS4XP15
Magnitude 2.0 · 1 study on file
Reported associations
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GENOME-WIDE GENE-SODIUM INTERACTION ANALYSES ON BLOOD PRESSURE: THE GENSALT STUDY - Unknown journal (n.d.) · Unknown authors · PubMed 27271309
ABSTRACT: We performed genome-wide analyses to identify genomic loci that interact with sodium to influence blood pressure (BP) using single marker (one and two degree-of-freedom joint tests) and gene-based tests among 1,876 Chinese participants of the Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study. Among GenSalt participants, the average of three urine samples was used to estimate sodium excretion. Nine BP measurements were taken using a random-zero-sphygmomanometer. A total of 2.05 million SNPs were imputed using Affymetrix 6.0 genotype data and the Chinese Han of Beijing and Japanese of Tokyo HapMap reference panel. Promising findings (P <1.00×10−4) from GenSalt were evaluated for replication among 775 Chinese participants of the Multi-ethnic Study of Atherosclerosi
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