rs11083866 - RN7SL340P - VSTM2B-DT

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N=1345 young and elderly subjects - Unknown journal (n.d.) · Unknown authors · PubMed 22903471

  ABSTRACT: Deficits in lentiform nucleus volume and morphometry are implicated in a number of genetically influenced disorders, including Parkinson's disease, schizophrenia, and ADHD. Here we performed genome-wide searches to discover common genetic variants associated with differences in lentiform nucleus volume in human populations. We assessed structural MRI scans of the brain in two large genotyped samples: the Alzheimer's Disease Neuroimaging Initiative (ADNI; N=706) and the Queensland Twin Imaging Study (QTIM; N=639). Statistics of association from each cohort were combined meta-analytically using a fixed-effects model to boost power and to reduce the prevalence of false positive findings. We identified a number of associations in and around the flavin-containing monooxygenase (FM

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