rs11083271 - CDH2 - ARIH2P1

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-Wide Association Study Identifies Variants Associated with Histologic Features of Nonalcoholic Fatty Liver Disease - Unknown journal (n.d.) · Unknown authors · PubMed 20708005

  ABSTRACT: Background & Aims There is little data available from genome-wide association studies (GWAS) of liver histology in patients with non-alcoholic fatty liver disease (NAFLD). We conducted a pilot GWAS in patients with NAFLD, characterized by histology, who were enrolled in the NASH CRN Database Study. Methods We studied clinical, laboratory, and histological data from 236 non-Hispanic Caucasian women with NAFLD. We analyzed 324,623 single nucleotide polymorphisms (SNPs) from the 22 autosomal chromosomes. Multivariate-adjusted logistic regression analyses were conducted for binary outcomes and linear regression analysis was applied for quantitative traits. A P-value < 1×10−6 was considered to be significant. Results In multivariate models adjusted for age, body mass index, diabete

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