rs11069071 - LINC02423 - LINC02440

Magnitude 2.8 · 1 study on file

Reported associations

• Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population - Unknown journal (n.d.) · Unknown authors · PubMed 31476763

  ABSTRACT: Suicide is a significant public health problem worldwide, and several Asian countries including Japan have relatively high suicide rates on a world scale. Twin, family, and adoption studies have suggested high heritability for suicide, but genetics lags behind due to difficulty in obtaining samples from individuals who died by suicide, especially in non-European populations. In this study, we carried out genome-wide association studies combining two independent datasets totaling 746 suicides and 14,049 non-suicide controls in the Japanese population. Although we identified no genome-wide significant single-nucleotide polymorphisms (SNPs), we demonstrated significant SNP-based heritability (35-48%; P < 0.001) for completed suicide by genomic restricted maximum-likelihood ana

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