rs1106475 - AFAP1L2

Magnitude 4.5 · 1 study on file

Reported associations

• Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population - Unknown journal (n.d.) · Unknown authors · PubMed 29212154

  ABSTRACT: Background Although the association of single nucleotide polymorphisms (SNPs) with metabolic syndrome (MetS) has been reported in various populations in several genome-wide association studies (GWAS), the data is not conclusive. In this GWAS study, we assessed whether SNPs are associated with MetS and its individual components independently and/or through complex interactions in a Taiwanese population. Methods A total of 10,300 Taiwanese subjects were assessed in this study. Metabolic traits such as waist circumference, triglyceride, high-density lipoprotein (HDL) cholesterol, systolic and diastolic blood pressure, and fasting glucose were measured. Results Our data showed an association of MetS at the genome-wide significance level (P < 8.6 x 10-8) with two SNPs, including the r

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