rs11059753 - TMEM132C

Magnitude 2.0 · 1 study on file

Reported associations

• Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank - Unknown journal (n.d.) · Unknown authors · PubMed 32564518

  ABSTRACT: Abstract Background Herpes simplex virus‐1 (HSV‐1) infection is reported to be associated with depression. But limited efforts were made to investigate the relationship between HSV‐1 infection and the risk of depression, especially from the genetic perspective. Methods In UK Biobank cohort, linear and logistic regression analyses were first performed to test the association of HSV‐1 seropositivity/antibody with depression, including depression status (N = 2951) and Patient Health Questionnaire (PHQ) score (N = 2839). Using individual genotypic and phenotypic data from the UK Biobank, genome‐wide environmental interaction study (GWEIS) was then conducted by PLINK2.0 to evaluate gene × HSV‐1 interacting effect on the risk of depression. Finally, gene set enrichment

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