rs11038339 - PRDM11

Magnitude 2.0 · 1 study on file

Reported associations

• Multivariate genome-wide analysis of education, socioeconomic status, and brain phenome - Unknown journal (n.d.) · Unknown authors · PubMed 33349686

  ABSTRACT: Socioeconomic status (SES) and education (EDU) are phenotypically associated with psychiatric disorders and behaviors. It remains unclear how these associations influence genetic risk for psychopathology, psychosocial factors, and EDU/SES individually. Using information from >1 million individuals, we conditioned the genetic risk for psychiatric disorders, personality traits, brain imaging phenotypes, and externalizing behaviors with genome-wide data for EDU/SES. Accounting for EDU/SES significantly affected the observed heritability of psychiatric traits ranging from 2.44% h2 decrease for bipolar disorder to 14.2% h2 decrease for Tourette syndrome. Neuroticism h2 significantly increased by 20.23% after conditioning with SES. After EDU/SES conditioning, neuronal cell-types were i

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