rs11037480 - HBE1, OR51I2, OR51B5, HBG2

Magnitude 2.2 · 1 study on file

Reported associations

• Lifestyle Factors and Genetic Variants on 2 Biological Age Measures: Evidence From 94 443 Taiwan Biobank Participants. - The journals of gerontology. Series A, Biological sciences and medical sciences (2022) · Lin WY · PubMed 34427645

  Biological age (BA) can be estimated by phenotypes and is useful for predicting life span and health span. Levine et al. proposed a PhenoAge and a BioAge to measure BA. Although there have been studies investigating the genetic predisposition to BA acceleration in Europeans, little has been known regarding this topic in Asians. I have estimated PhenoAgeAccel (age-adjusted PhenoAge) and BioAgeAccel (age-adjusted BioAge) of 94 443 Taiwan Biobank (TWB) participants, wherein 25 460 TWB1 participants formed a discovery cohort and 68 983 TWB2 individuals constructed a replication cohort. Lifestyle factors and genetic variants associated with PhenoAgeAccel and BioAgeAccel were investigated through regression analysis and a genome-wide association study. A unit (kg/m2) increase of body mass index

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