rs10994278 - ANK3

Magnitude 2.2 · 1 study on file

Reported associations

• Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits - Unknown journal (n.d.) · Unknown authors · PubMed 31553412

  ABSTRACT: Key Points Question Is the genetic liability to psychotic experiences shared with schizophrenia and/or other neuropsychiatric disorders and traits? Findings In this cohort study, genetic correlation, polygenic risk score, and copy number variation analyses indicated a shared genetic liability between psychotic experiences and major depressive disorder, schizophrenia, bipolar disorder, and neurodevelopmental disorders. Genome-wide association studies identified 4 genetic loci associated with psychotic experiences including loci in ANK3 and CNR2. Meaning Findings suggest that the genetic liability of psychotic experiences is shared with several psychiatric disorders, which include, but is not specific to, schizophrenia. Importance Psychotic experiences, such as hallucinations and d

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