rs10972350 - ATOSB - UNC13B

Magnitude 2.2 · 1 study on file

Reported associations

• A Genome-Wide Interaction Study of Erythrocyte ω-3 Polyunsaturated Fatty Acid Species and Memory in the Framingham Heart Study Offspring Cohort. - The Journal of nutrition (2024) · Annevelink CE, Westra J, Sala-Vila A, Harris WS, Tintle NL, Shearer GC · PubMed 38141771

  Cognitive decline, and more specifically Alzheimer's disease, continues to increase in prevalence globally, with few, if any, adequate preventative approaches. Several tests of cognition are utilized in the diagnosis of cognitive decline that assess executive function, short- and long-term memory, cognitive flexibility, and speech and motor control. Recent studies have separately investigated the genetic component of both cognitive health, using these measures, and circulating fatty acids. We aimed to examine the potential moderating effect of main species of ω-3 polyunsaturated fatty acids (PUFAs) on an individual's genetically conferred risk of cognitive decline. The Offspring cohort from the Framingham Heart Study was cross-sectionally analyzed in this genome-wide interaction study (GW

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