rs10962181 - RNA5SP279 - SMARCA2

Magnitude 4.5 · 1 study on file

Reported associations

• Common variants at 1p36 are associated with superior frontal gyrus volume - Unknown journal (n.d.) · Unknown authors · PubMed 25335168

  ABSTRACT: The superior frontal gyrus (SFG), an area of the brain frequently found to have reduced gray matter in patients with schizophrenia, is involved in self-awareness and emotion, which are impaired in schizophrenia. However, no genome-wide association studies of SFG volume have investigated in patients with schizophrenia. To identify single-nucleotide polymorphisms (SNPs) associated with SFG volumes, we demonstrated a genome-wide association study (GWAS) of gray matter volumes in the right or left SFG of 158 patients with schizophrenia and 378 healthy subjects. We attempted to bioinformatically ascertain the potential effects of the top hit polymorphism on the expression levels of genes at the genome-wide region. We found associations between five variants on 1p36.12 and the right SF

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