rs10960765 - LURAP1L-AS1

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability - Unknown journal (n.d.) · Unknown authors · PubMed 29662168

  ABSTRACT: Hair color is one of the most recognizable visual traits in European populations and is under strong genetic control. Here we report the results of a genome-wide association study meta-analysis of almost 300,000 participants of European descent. We identified 123 autosomal and one X-chromosome loci significantly associated with hair color; all but 13 are novel. Collectively, SNPs associated with hair color within these loci explain 34.6% of red hair, 24.8% of blond hair and 26.1% of black hair heritability in the study populations. These results confirm the polygenic nature of complex phenotypes and improve our understanding of melanin pigment metabolism in humans. FULL TEXT: [INTRO] Human pigmentation refers to coloration of external tissues due to variations in quantity, ratio

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