rs10952077 - UNCX - MICALL2

Magnitude 2.2 · 1 study on file

Reported associations

• Novel genetic loci of inhibitory control in ADHD and healthy children and genetic correlations with ADHD. - Progress in neuro-psychopharmacology & biological psychiatry (2024) · Pang T, Ding N, Zhao Y, Zhao J, Yang L, Chang S · PubMed 38430954

  Cumulative evidence has showed the deficits of inhibitory control in patients with attention deficit hyperactivity disorder (ADHD), which is considered as an endophenotype of ADHD. Genetic study of inhibitory control could advance gene discovery and further facilitate the understanding of ADHD genetic basis, but the studies were limited in both the general population and ADHD patients. To reveal genetic risk variants of inhibitory control and its potential genetic relationship with ADHD, we conducted genome-wide association studies (GWAS) on inhibitory control using three datasets, which included 783 and 957 ADHD patients and 1350 healthy children. Subsequently, we employed polygenic risk scores (PRS) to explore the association of inhibitory control with ADHD and related psychiatric disord

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