rs10945918 - QKI - RN7SL366P

Magnitude 4.5 · 1 study on file

Reported associations

• Single nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases - Unknown journal (n.d.) · Unknown authors · PubMed 30120429

  ABSTRACT: Background/Objectives Obesity is an important risk factor for the development of diseases such as diabetes mellitus, hypertension, and dyslipidemia; however, a small number of individuals with long-standing obesity do not present with these cardiometabolic diseases. Such individuals are referred to as metabolically healthy obese (MHO) and potentially represent a subgroup of the general population with a protective genetic predisposition to obesity-related diseases. We hypothesized that individuals who were metabolically healthy but significantly obese (BMI ≥35 kg/m2) would represent a highly homogenous subgroup, with which to investigate potential genetic associations to obesity. We further hypothesized that such a cohort may lend itself well to investigate potential genotypes

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