rs10919791 - RNU6-778P - RNU6-716P

Magnitude 2.8 · 1 study on file

Reported associations

• Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer - Unknown journal (n.d.) · Unknown authors · PubMed 25086665

  ABSTRACT: We performed a multistage genome-wide association study (GWAS) including 7,683 individuals with pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome-wide significance: rs6971499 at 7q32.3 (LINC-PINT; per-allele odds ratio [OR] = 0.79; 95% confidence interval [CI] = 0.74-0.84; P = 3.0×10−12), rs7190458 at 16q23.1 (BCAR1/CTRB1/CTRB2; OR = 1.46; 95% CI = 1.30-1.65; P = 1.1×10−10), rs9581943 at 13q12.2 (PDX1; OR = 1.15; 95% CI = 1.10-1.20; P = 2.4×10−9), and rs16986825 at 22q12.1 (ZNRF3; OR = 1.18; 95% CI = 1.12-1.25; P = 1.2×10−8). An independent signal was identified in exon 2 of TERT at the established region 5p15.33 (rs2736098; OR = 0.80; 95% CI = 0.76-0.85; P = 9.8×10−14). We also identified a locus at 8q24.21 (rs156192

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