rs10895575 - PDGFD

Magnitude 2.2 · 1 study on file

Reported associations

• Genome wide association study identifies four loci for early onset schizophrenia - Unknown journal (n.d.) · Unknown authors · PubMed 33907183

  ABSTRACT: Early onset schizophrenia (EOS, defined as first onset of schizophrenia before age 18) is a rare form of schizophrenia (SCZ). Though genome-wide association studies (GWASs) have identified multiple risk variants for SCZ, most of the cases included in these GWASs were not stratified according to their first age at onset. To date, the genetic architecture of EOS remains largely unknown. To identify the risk variants and to uncover the genetic basis of EOS, we conducted a two-stage GWAS of EOS in populations of Han Chinese ancestry in this study. We first performed a GWAS using 1,256 EOS cases and 2,661 healthy controls (referred as discovery stage). The genetic variants with a P < 1.0 × 10−04 in discovery stage were replicated in an independent sample (903 EOS cases and

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