rs10887741 - PAPSS2
Magnitude 2.8 · 1 study on file
Reported associations
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Genome-wide Association Study of Exercise Behavior in Dutch and American Adults - Unknown journal (n.d.) · Unknown authors · PubMed 19727025
ABSTRACT: Introduction The objective of this study was to identify genetic variants that are associated with adult leisure-time exercise behavior using genome-wide association in two independent samples. Methods Exercise behavior was measured in 1,772 unrelated Dutch and 978 unrelated American adults with detailed questions about type, frequency and duration of exercise. Individuals were classified into regular exercisers or non-exercisers using a threshold of 4 METhours (metabolic equivalents*hours per week). Regular exercisers were further divided into 5 categories of METhours, ranging from moderate (>=4 METhours) to highly vigorous (>=40 METhours) exercisers. Genome-wide association analyses with a total of 470,719 SNPs were conducted in both samples independently using regression-based
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Exercise
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regular physical activity engagement Moderate
PAPSS2 T allele associated with increased leisure-time exercise behavior; gene expressed in peripheral nerve and adipose tissues relevant to exercise physiology
150+ minutes weekly moderate-intensity aerobic activity or 2-3 resistance training sessions