rs10867821 - TLE1-DT - RNA5SP287

Magnitude 4.5 · 1 study on file

Reported associations

• A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion. - Journal of human genetics (2021) · Zhu Z, Chen B, Na R, Fang W, Zhang W, Zhou Q, Zhou S, Lei H, Huang A, Chen T, Ni D, Gu Y, Liu J, Rao Y, Fang F · PubMed 32939015

  The Ebbinghaus illusion (EI) is an optical illusion of relative size perception that reflects the contextual integration ability in the visual modality. The current study investigated the genetic basis of two subtypes of EI, EI overestimation, and EI underestimation in humans, using quantitative genomic analyses. A total of 2825 Chinese adults were tested on their magnitudes of EI overestimation and underestimation using the method of adjustment, a standard psychophysical protocol. Heritability estimation based on common single nucleotide polymorphisms (SNPs) revealed a moderate heritability (34.3%) of EI overestimation but a nonsignificant heritability of EI underestimation. A meta-analysis of two phases (phase 1: n = 1986, phase 2: n = 839) of genome-wide association study (GWAS)

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